CASPR2 positive autoimmune encephalitis presenting as delirium in an alcohol dependent patient: a diagnostic dilemma

Authors

  • Arya Jith Assistant Professor, Department of Psychiatry, Amrita Institute of Medical sciences, Kochi Author
    • Kathleen Anne Mathew Senior Resident, Department of Psychiatry, Amrita Institute of Medical Sciences, Kochi Author
      • Dinesh Narayanan Professor and Head, Department of Psychiatry, Amrita Institute of Medical Sciences, Kochi Author
        • Sheen Maria Jacob Junior Resident, Department of psychiatry, Amrita Institute of Medical Sciences, Kochi Author

          DOI:

          https://doi.org/10.30834/KJP.34.1.2021.265

          Keywords:

          Delirium, autoimmune encephalitis, alcohol withdrawal, CASPR2

          Abstract

          Delirium, a major psychiatric emergency commonly encountered in alcohol withdrawal state, can have various aetiologies. Here we present a case of protracted delirium in an alcohol dependent patient, which on detailed neurological workup was diagnosed to be autoimmune encephalitis with CASPR2 (contactin-associated protein-like 2) antibodies. Subsequent treatment with immunotherapy and steroids lead to the resolution of symptoms.

           

          References

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          Published

          07-06-2021

          Issue

          Vol. 34 No. 1 (2021): Jan-Jun 2021

          Section

          Case Report

          License

          Copyright (c) 2021 Kerala Journal of Psychiatry

          Creative Commons License

          This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

          How to Cite

          1.
          CASPR2 positive autoimmune encephalitis presenting as delirium in an alcohol dependent patient: a diagnostic dilemma. Kerala Journal of Psychiatry [Internet]. 2021 Jun. 7 [cited 2026 Aug. 1];34(1):54-6. Available from: https://kjponline.com/index.php/kjp/article/view/265

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