CASPR2 positive autoimmune encephalitis presenting as delirium in an alcohol dependent patient: a diagnostic dilemma

Authors

  • Arya Jith Assistant Professor, Department of Psychiatry, Amrita Institute of Medical sciences, Kochi
  • Kathleen Anne Mathew Senior Resident, Department of Psychiatry, Amrita Institute of Medical Sciences, Kochi
  • Dinesh Narayanan Professor and Head, Department of Psychiatry, Amrita Institute of Medical Sciences, Kochi
  • Sheen Maria Jacob Junior Resident, Department of psychiatry, Amrita Institute of Medical Sciences, Kochi

DOI:

https://doi.org/10.30834/KJP.34.1.2021.265

Keywords:

Delirium, autoimmune encephalitis, alcohol withdrawal, CASPR2

Abstract

Delirium, a major psychiatric emergency commonly encountered in alcohol withdrawal state, can have various aetiologies. Here we present a case of protracted delirium in an alcohol dependent patient, which on detailed neurological workup was diagnosed to be autoimmune encephalitis with CASPR2 (contactin-associated protein-like 2) antibodies. Subsequent treatment with immunotherapy and steroids lead to the resolution of symptoms.

 

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References

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Published

07-06-2021

How to Cite

Jith, A., K. A. Mathew, D. . Narayanan, and S. M. . Jacob. “CASPR2 Positive Autoimmune Encephalitis Presenting As Delirium in an Alcohol Dependent Patient: A Diagnostic Dilemma”. Kerala Journal of Psychiatry, vol. 34, no. 1, June 2021, pp. 54-56, doi:10.30834/KJP.34.1.2021.265.

Issue

Section

Case Report