Kallmann Syndrome and Depression: A Case Report
DOI:
https://doi.org/10.30834/KJP.38.1.2025.509Keywords:
Kallmann syndrome, Hypogonadotrophic hypogonadism, Testosterone, DepressionAbstract
Kallmann syndrome is a genetic condition that causes low testosterone levels and anosmia. It can also be linked to mood disorders such as depression. This case report describes an 18-year-old male with Kallmann syndrome who experienced low mood, fatigue, irritability, and sleep disturbances. He was receiving testosterone therapy and was started on Escitalopram and Clonazepam for depression. His symptoms initially improved, but after stopping both testosterone and antidepressants, his depression returned. Restarting Escitalopram led to symptom improvement. This case highlights the need for regular psychiatric evaluation in patients with Kallmann syndrome, as stopping treatment can lead to a relapse of depressive symptoms. Early recognition and proper management can improve patient well-being.
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Copyright (c) 2025 Tanvi Mittal, Nishanth JH (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
