Propofol Induced Seizure like Phenomenon During Modified Electroconvulsive Therapy

Authors

  • Divya R Nair Assistant Professor,Department Of Psychiatry,Father Muller Medical College,Mangalore,Karnataka
  • Rajmohan Velayudhan Professor, Department of Psychiatry, KMCT Medical College, Kerala https://orcid.org/0000-0002-5468-2305
  • Raghuram Thazhe Mangool Emeritus Professor, Department Of Psychiatry,MES Medical College,Perinthalmanna,Kerala
  • Ajith Premnath Associate Professor,Department Of Psychiatry,MES Medical College,Perinthalmanna,Kerala

DOI:

https://doi.org/10.30834/KJP.37.2.2024.466

Keywords:

Propofol, Seizure, Seizure like phenomenon (SLP), Modified Elecroconvulsive Therapy (MECT)

Abstract

Background: Propofol is an intravenous anesthetic that is said to have anticonvulsant properties. This is a case report of the propofol-induced seizure-like phenomenon (SLP) during modified (MECT).

Case Report: A 24-year-old female with severe depression without psychotic symptoms and borderline personality disorder underwent six sessions of MECT. During the earlier session of MECT using thiopentone as an anesthetic, a prolonged seizure occurred, indicating a low seizure threshold. Then, it was changed to propofol. When propofol was given as an induction agent, even before giving ECT, the patient developed seizure-like involuntary jerking movements.  EEG and MRI were done after the fourth session and were found normal.

Discussion: This case report highlights that even though propofol has anticonvulsant activity, few cases of SLP during procedures have been reported. Propofol-induced SLP during MECT is the first of its kind.

 

 

Conflict of Interest: Rajmohan Velayudhan: The article was submitted on 30 July 2024. On 12 August, the author became editor-in-chief of the Journal. Adhering to COPE Guidelines, the previous editor and section editor processed and decided on the article. The current editor-in-chief was not involved in any processing or decision-making phase.

The other authors have no conflict of interest. 

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References

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Published

18-12-2024

How to Cite

Divya R Nair, Rajmohan Velayudhan, Raghuram Thazhe Mangool, and Ajith Premnath. “Propofol Induced Seizure Like Phenomenon During Modified Electroconvulsive Therapy”. Kerala Journal of Psychiatry, Dec. 2024, doi:10.30834/KJP.37.2.2024.466.

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Section

Case Report