Effect of adjunctive music listening in schizophrenia – a randomized controlled trial


  • A Jeyan S M Clinic, 7-C Chettipalayam Road, Podanur (PO), Coimbatore – 641023 Tamilnadu India
  • Nair V Indu Senior Consultant, Mental Health Centre , Thiruvanananthapuram
  • B Sivaprakash Mahatma Gandhi Medical College and Research Institute, Pondicherry
  • K Banipreet S M Clinic, 7-C Chettipalayam Road, Podanur (PO), Coimbatore – 641023 Tamilnadu India




: schizophrenia, music listening, acute phase, symptom reduction, drug dose requirements


Background: Music-based interventions are currently being researched for their effectiveness in schizophrenia. Very few studies have been done in the acute phase. Further, there is a dearth of published Indian research in this context. Methods: A prospective, randomized, controlled, single-blind study was done in a tertiary psychiatric hospital in South India from October-2015 to March-2016. Immediately after admission, consenting adult patients with schizophrenia were randomly assigned to two groups. Over four weeks, Group-A(N=51) received 20 sessions of music-listening as an add-on to standard care, and Group-B(N=53) received standard care alone. Reduction in Positive and Negative Syndrome Scale (PANSS) scores and the drug dosage requirements for both groups were compared. Statistical analysis was done using two-way repeated-measures ANOVA for PANSS score reduction and Mann-Whitney U for drug dosage comparison. Results: We observed a greater decrease in PANSS scores in Group-A than Group B, but this difference did not reach significance (p>0.05 for all three subscales and total score). Group-A required lesser risperidone-equivalent doses than Group-B, but this was not significant (p=0.27). However, Group-A required significantly lesser diazepam equivalent (p=0.003) and trihexyphenidyl (p=0.007) doses than Group-B. Conclusions:  The above findings suggest a possible additional benefit of adding music listening to standard care for the acute phase management of schizophrenia and reducing drug dosage requirements. Music-based interventions for schizophrenia warrant further research, especially in the Indian context and wider application in clinical practice.


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How to Cite

Jeyan , A., Indu, N. V., Sivaprakash, B., & Banipreet, . K. (2022). Effect of adjunctive music listening in schizophrenia – a randomized controlled trial. Kerala Journal of Psychiatry, 35(1), 47–53. https://doi.org/10.30834/KJP.35.1.2022.316



Research Report