Darier's disease and Schizophrenia- A case report

Rahul Thovarayi; V Nair Indu; Babu Kiran

doi:10.30834/KJP.34.1.2021.274

Authors

Rahul Thovarayi DNB Resident, Psychiatry, Mental Health Centre, Thiruvananthapuram
V Nair Indu Senior Consultant, Psychiatry, Mental Health Center, Thiruvananthapuram
Babu Kiran DNB Resident, Psychiatry, Mental Health Centre, Thiruvananthapuram

DOI:

https://doi.org/10.30834/KJP.34.1.2021.274

Keywords:

Darier's disease, Schizophrenia

Abstract

Darier's disease is a rare autosomal dominant genodermatosis. There is a specific mutation in the ATP2A2 gene on chromosome 12q. Several neuropsychiatric manifestations have been described in association with Darier's disease. Most reports have come from western populations, with limited reports of Darier's disease and its neuropsychiatric associations among Asian people, although the demographic and clinical profiles are comparable. We present a case of 38 year old female from Kerala with Darier's disease presenting with schizophrenia spectrum disorder. Her first degree relatives have schizophrenia-like psychosis and dermatological manifestations suggestive of Darier's disease.

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