A Case of Acute Psychosis Following Normalisation of Thyroid Status with Propylthiouracil in Long-standing Hyperthyroidism

Authors

  • Tom Ansumol Government Medical College, Ernakulam
  • Chacko Deenu Government Medical College, Ernakulam
  • Karunakaran Vidhukumar Government Medical College, Ernakulam

DOI:

https://doi.org/10.30834/KJP.30.2.2017.123

Keywords:

hyperthyroidism, acute psychosis, propylthiouracil

Abstract

Precipitation of acute psychosis following normalisation of thyroid status has been reported previously. Here, we report the case of a 62-year-old man with long-standing hyperthyroidism unresponsive to carbimazole, developing acute polymorphic psychotic disorder without symptoms of schizophrenia, along with normalization of thyroid status, after seven months of treatment with propylthiouracil.

Downloads

Download data is not yet available.

References

Benvenga S, Lapa D, Trimarchi F. Dont forget the thyroid in the etiology of psychoses. Am J Med. 2017 Dec;115(2):159–60.

Gowda G, Sagi M, Komal S, Jaisoorya T. Psychosis following carbimazole-induced acute alteration of hyperthyroid status. Indian J Psychol Med. 2017;39(4):516.

Sharma P, Parmar C, Parikh N. A case report on myxedema madness: Curable psychosis. Indian J Psychol Med. 2014;36(1):80.

Santos NC, Costa P, Ruano D, MacEdo A, Soares MJ, Valente J, et al. Revisiting thyroid hormones in schizophrenia. Vol. 2012, Journal of Thyroid Research. 2012.

Zhang J, Lazar M a. The mechanism of action of thyroid hormones. Annu Rev Physiol. 2000;62(1):439–66.

Turan T. Thyroid hormones and psychiatric disorders. Klin Psikofarmakol Bul. 2011;21:S76–7.

Manuscript A, Phenotypes I. NIH Public Access. 2011;34(5):689–700.

Irwin R, Ellis PM, Delahunt J. Case report Psychosis following acute alteration of thyroid. 2015;

M.D. SAF. Radioactive Iodine-Induced Psychosis. Am J Psychiatry. 2009;166(9):1067–8.

Propylthiouracil and Acute psychosis - from FDA reports, https://www.ehealthme.com/ds/propylthiouracil/acute-psychosis/,12/15/2017.

Downloads

Published

06-03-2018

How to Cite

Ansumol, T., C. Deenu, and K. Vidhukumar. “A Case of Acute Psychosis Following Normalisation of Thyroid Status With Propylthiouracil in Long-Standing Hyperthyroidism”. Kerala Journal of Psychiatry, vol. 30, no. 2, Mar. 2018, pp. 90-92, doi:10.30834/KJP.30.2.2017.123.